USS Indiana ndiyo yikaŵa yakwamba mu gulu lake ndipo yikaŵa yakwamba kuyana na sitima za nkhondo za ku vyaru vinyake. Sitimayi yikalembeka mu 1890 ndipo yikamba kugwira ntchito pakati pajumpha vyaka vinkhondi. Kweniso boti ili likaŵa lakwamba kugwiliskira nchito batire. Ngalaŵa iyi yikapangika kuti yivikilirenge virwa vya mumphepete mwa nyanja.

Indiana wakateŵetera mu Nkhondo ya ku Spain na America (1898) nga ni chigaŵa cha North Atlantic Squadron. Chikaŵaso mu Nkhondo ya ku Santiago de Cuba, iyo yikachitika apo ŵasilikari ŵa ku Spain ŵakayezga kuti ŵajumphe. Nangauli yikaleka kulondezga sitima za ku Spain, kweni yikaparanya sitima za ku Spain za Plutón na Furor. Nkhondo yikati yamara, yikaleka kugwira ntchito nangauli yikaŵa kuti yikasintha vinandi. Mu Janyuwale 1919, ŵakamuleka kachitatu na kaumaliro. Mu 1920, ŵakamubwangandura mu maji ghambura kukwera chomene, ndipo mu 1924 ŵakamuguliska.